|
Brands & Products:
| Searle |
Anavar (o.c.)
(US) |
2.5 mg
tabs |
|
Anatrophill (o.c.)
(FR) |
2.5 mg
tabs |
|
Lipidex
(Brazil) |
2.5 mg
tabs |
|
Lonavar (o.c.)
(Argentina) |
2.5 mg
tabs |
| Dainippon |
Lonavar
(Japan) |
2 mg tabs |
| Societta Prodotti
Antibiotica |
Oxandrolone SPA
(I) |
2.5 mg
tabs |
| Kowa |
Vasorome
(Japan) |
0.5 and 2 mg
tabs |
| Ttokkyo Labs |
Oxandrolone |
5 mg tabs |
| BioTechnology General
(BTG) |
Oxandrin
(US) |
2.5 mg
tabs |
Characteristics:
AAn intrinsically weak steroid with a high
price-tag and low availability, oxandrolone owes its
large popularity due to its safety. In sharp contrast to
oxymetholone, oxandrolone is quite generally considered
to be the safest of all steroids. Its effects are more
than well-documented and have been for a few decades
now. The medical community values oxandrolone as a safe
alternative for more harmful steroids, which is why it
is considered safe for use in children and even in
patients suffering hepa-toxicity as the result of
alternate steroid use1.
It's most noted medical use has been in the
expediting of wound healing2,3 often
practically applied to the treatment of burns
4,5,6. But recently its gaining popularity
again as a means of keeping weight on HIV-infected
patients suffering from wasting due to the
immuno-deficiency virus. It was also considered safe for
use in prepubescent children with a growth
delay7. No major harmful effects were noted
from this particular therapy, eventhough one
study8 reported that the use of oxandrolone
did speed up the onset of puberty in these children.
Furthermore oxandrolone has found frequent applications
in the treatment of other wasting symptoms for hepatitis
and cancer as well as the treatment of osteoporosis in
both men and women of all ages.
Oxandrolone was introduced in the year 1964,
when Searle came out with the original Anavar. It
quickly became the popular drug in the sports crowd for
people looking for a safer alternative to the major
steroid at the time, Dianabol (methandrostenolone). It
remained one of the best-sellers for well over 2 decades
until it was indefinitely discontinued in the year 1989.
Much to the regret of the recreational bodybuilding and
powerlifting community. The prices have remained high
for the little stock that remained available. The only
brand readily found was oxandrolone SPA, manufactured in
Milano, Italy. That is, until 1995 when its use in the
treatment of the then vastly spreading immuno-deficiency
disease AIDS9 sparked the interest of BTG, a
US-based company who came out with Oxandrin. The first
widely available oxandrolone product since Anavar
production was stopped.
The main reasons for the wide-spread use of
oxandrolone in sports is because it is very appealing to
female athletes as well as male athletes. It causes
little or no virilization properties, demonstrated by
its medical uses to treat women. This is rather
surprising since oxandrolone does not aromatize either.
It's the only steroid that is both safe and convenient
without producing excess estrogen. That makes it
particularly useful when cutting up for a contest or
preventing an increase in body-fat due to estrogenic
effects. In fact the main use of oxandrolone to a
bodybuilder is in the maintenance of lean mass while
reducing body-fat. Oxandrolone itself may not actually
reduce body-fat, but it too plays a key role in the
process. Like most non-aromatizing compounds it has a
repressing effect on the appetite making it easier for
the user to control cravings and stay strict with his
diet.
Oxandrolone also has little effect on the
body's own natural hormone production. The negative
feedback was found to be very minor, meaning that during
short term use no suppression of Gonadotropin releasing
hormone (GnRH, start of natural testosterone production)
was noted. This meant that whatever gains made, as
little as they may have been, were very easily
maintained post-cycle. So there was also no use for
products like Clomid or Nolvadex in conjunction with
oxandrolone consumption. The easy to maintain low gains
would indicate a low binding to the androgen receptor.
While not extremely high, it should actually be noted
that it does have quite decent binding to the androgen
receptor. But the reason for its mild effects is quite
likely the low dose used. Rarely if ever are doses
higher than 20 mg used on a daily basis. Either because
of convenience or due to the high price. But comparing
that the doses of other steroids this is remarkably low.
So its only logical the gains and side-effects aren't
particularly notable.
Of course a bodybuilder has limited use for a
compound that is both a weak androgen in the doses
mostly used and doesn't aromatize since no mentionable
effect on mass can be produced to satisfy the chemically
enhanced athlete. Therefor it is best noted that
oxandrolone is most popular with power- and
weightlifters to enhance strength without increasing
bodyweight. This is valued highly since strength
athletes often compete in weight-classes. Oxandrolone
does not increase strength through androgenic
stimulation, at least not primarily. It stimulates the
formation of phosphocreatine, a body compound that can
replenish ATP (adenosine tri-phosphate) , the main
energy currency of the living organism. This gives an
incredible increase in short term anaerobic performance,
the type needed for explosive action such as sprinting
and lifting weight.
For bodybuilders the best results are seen
when stacking oxandrolone with a highly androgenic
compound. Either during a mass stack with aromatizable
products to boost strength a little more, or in
conjunction with a non-estrogenic compound. This is most
beneficial since it can maintain lean mass, decrease
appetite, improve sharpness of the muscle and keep
strength levels up without giving increased androgenic
risk (acne, prostate hypertrophy, hair loss) when
stacked with pure androgens (stanozolol, drostanolone).
For those looking for safe maintenance of muscle mass a
stack of Anavar with Primobolan is not a bad investment
(but a big investment). The common use of oxandrolone is
estimated, at 0.125 mg per pound of bodyweight. For men
it should be closer to 0.2 mg per pound, for women 0.08
mg per pound per day.
The downsides to oxandrolone are minor. The
worst problem by far is the poor availability and high
price. But it has to be noted that, eventhough
oxandrolone is nowhere near Halotestin or anadrol in
hepa-toxicity, it too is a 17-alpha-alkylated substance
that can cause liver damage if used for long periods on
end. Other common side-effects include headaches, loss
of libido, diarrhea and dizziness.
The conclusion to follow these paragraphs is
of course that oxandrolone is understandably still a
popular and very versatile steroid, much desired by both
experienced athletes and novice users because of its
many properties. While few will say this is the best or
their favorite steroid, you won't find many that will
have anything negative to say about it either.
Stacking and
Use:
Because of its mild nature and the low doses
generally used with oxandrolone there is very little use
for secondary compounds like anti-aromatase drugs,
estrogen receptor antagonists or blood pressure
medication. That in itself may somewhat make up for the
high cost and little gains made on it.
In stacks Anavar is sometimes used to increase
strength or help maintain it during mass phases.
Oxandrolone obviously has very little to add in terms of
mass compared to the other substances used to obtain
such goals. It fades in comparison to test, Deca,
Anadrol, D-bol and such. Nonetheless it is added quite
often, perhaps because people assume it will make the
overall stack less hazardous, but that's a myth of
course. Frankly I would imagine there are better and
cheaper things to waste your money on if mass is what
you seek.
On a cutting phase oxandrolone makes a good
match for 120-140 mcg of clenbuterol daily stacked with
something in the nature of Halotestin or Winstrol. The
combination improves muscle hardness and striation as
well as support mass and strength retention. Experienced
users would preferably add testosterone propionate or
Equipoise no doubt, rather than Halotestin or Winstrol
due to less hazard to the liver associated with those
two drugs, especially Halotestin.
Mostly it is used for decent strength gains
without gaining too much weight, particularly suited for
weight- and powerlifters and martial artists. In that
aspect, and in my humble opinion, Winstrol would be a
good choice for a stack. 50 mg of Winstrol every day to
every other day stacked with 30-40 mg of oxandrolone
daily would give a very good result in overall strength
enhancement without adding a mentionable amount of
weight to the frame.
References
1 Segal S, Cooper J, Bolognia J., Treatment of
lipodermatosclerosis with oxandrolone in a patient with
stanozolol-induced hepatotoxicity., J Am Acad Dermatol
2000 Sep;43(3):558-9
2 Demling RH., Oxandrolone, an anabolic steroid,
enhances the healing of a cutaneous wound in the rat.,
Wound Repair Regen 2000 Mar-Apr;8(2):97-102
3 Demling RH, Orgill DP., The anticatabolic and wound
healing effects of the testosterone analog oxandrolone
after severe burn injury., J Crit Care 2000
Mar;15(1):12-7
4 Hart DW, Wolf SE, Ramzy PI, Chinkes DL, Beauford
RB, Ferrando AA, Wolfe RR, Herndon DN., Anabolic effects
of oxandrolone after severe burn., Ann Surg 2001
Apr;233(4):556-64
5 Demling RH, DeSanti L., The rate of restoration of
body weight after burn injury, using the anabolic agent
oxandrolone, is not age dependent., Burns 2001
Feb;27(1):46-51
6 Demling RH, DeSanti L., Oxandrolone, an anabolic
steroid, significantly increases the rate of weight gain
in the recovery phase after major burns., J Trauma 1997
Jul;43(1):47-51
7 Papadimitriou A, Preece MA, Rolland-Cachera MF,
Stanhope R., The anabolic steroid oxandrolone increases
muscle mass in prepubertal boys with constitutional
delay of growth., J Pediatr Endocrinol Metab 2001
Jun;14(6):725-7
8 Doeker B, Muller-Michaels J, Andler W, Induction of
early puberty in a boy after treatment with oxandrolone?
Horm Res 1998;50(1):46-8
9 James JS., Wasting syndrome: oral oxandrolone
re-released in U.S., AIDS Treat News 1995 Dec 22;(no
237):3-4
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Anavar
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